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Extracellular Matrix Proteins: Implications for Angiogenesis

Show simple item record Williams, Kent Edward 2010-07-20T18:06:59Z 2015-10-01T13:47:31Z 2010-07-20T18:06:59Z 2015-10-01T13:47:31Z 2010-07-20T18:06:59Z
dc.description.abstract The extracellular matrix (ECM) is an essential requirement for maintaining permanent shape and rigidity in multicellular organisms. The ECM serves two main functions: scaffolding and signaling. Insoluble collagen and soluble proteoglycans, glycosaminoglycans (GAGs), and glycoproteins allow for water retention and flexibility. The signaling role of the ECM is essential for a multitude of events including vascular development and angiogenesis. Via interactions with vascular endothelial cells, proteins of the ECM can induce or repress angiogenesis.
dc.description.statementofresponsibility Kent Edward Williams
dc.language.iso en_US
dc.subject.lcsh Neovascularization inhibitors.
dc.subject.lcsh Extracellular matrix.
dc.subject.lcsh Vascular endothelial growth factors.
dc.subject.other Angiogenesis inhibitors.
dc.title Extracellular Matrix Proteins: Implications for Angiogenesis
dc.type Thesis May 2010
dc.description.committeechair Albig, Allan
dc.description.committeemembers Swapan Ghosh
dc.description.committeemembers Diana Hews Master of Science
dc.description.department Department of Biology
dc.description.imprint Cunningham Memorial library, Terre Haute,Indiana State University
dc.description.itemidetd GS071610-201001
dc.description.level Masters
dc.description.note Title from document title page. Document formatted into pages: contains 65 p.: ill. Includes abstract .

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